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Publications

Management of forced smoking cessation among pregnant smokers because of the smoking ban at maternity hospitals in Pays de la Loire
2 juil. 2025 02:00 - SFR Icat
CONCLUSIONS: The management of smoking cessation in pregnant smokers in France is not optimal. Healthcare professionals should be trained and a national protocol should be introduced to improve the quality of care given to hospitalised pregnant smokers.
Editorial
30 juin 2025 02:00 - SFR Icat
No abstract
Etiologic Diagnosis of Neuropathies Based on First-Line Screening of TTR Gene Mutations
30 juin 2025 02:00 - SFR Icat
BACKGROUND: Hereditary amyloid transthyretin (ATTRv) is caused by TTR gene mutations, which lead to multisystem amyloid deposits. A misdiagnosis is common, which delays treatment. We assessed the prevalence of TTR mutations in patients with neuropathy of unknown cause at the first stage of assessment.
Detection, evaluation and management of the sequelae of infectious encephalitis in adults
28 juin 2025 02:00 - SFR Icat
No abstract
Neuropathy in GAA-FGF14 Late-Onset Cerebellar Ataxia (SCA27B): Prevalence and Characteristics
28 juin 2025 02:00 - SFR Icat
CONCLUSIONS: The prevalence of neuropathy in SCA27B patients was similar to that reported in the elderly general population. Neuropathies were predominantly non-specific length-dependent axonal neuropathies, primarily driven by aging and known risk factors rather than the underlying genetic abnormality.
Doxorubicin-NFL-TBS.40-63 peptide Gold Complex Nanovector (DOX IN-NFL@AuNPs): Efficacy Evaluation in a mouse transplantation tumor model induced by PANC-1/ADR human pancreatic cancer resistant strain cells
26 juin 2025 02:00 - SFR Icat
The key role of the NFL-TBS.40-63 peptide (BIOT-NFL) is to target and destroy glioma cancer cells. Recently we have performed a novel peptide-hybrid-gold nanovector (BIOT-NFL-PEG-AuNPs) capable to destroy microtubule network of pancreatic cancer cells (PDAC) exhibiting a decrease of tumor index with a real anti-angiogenic effect. In order to improve the scientific background of our study, we conceived a chemotherapeutic hybrid nanovector based on gold-doxorubicin (DOX) functionalized with the...
Shprintzen-Goldberg syndrome: follow-up of the cardiovascular features in an international cohort of 29 patients with SGS
25 juin 2025 02:00 - SFR Icat
CONCLUSION: Patients with SGS also significantly have cardiovascular manifestations, encouraging the implementation of a follow-up and preventive cardiovascular treatment identical to that of MFS.
Using Foams for the Oxidative Dissolution of Copper Particles: Transport of Reactants Is Controlled by the Foam Structure
24 juin 2025 02:00 - SFR Icat
We study the oxidation of micrometric copper particles in rotating aqueous foams by oxygen O(2) present in the gas bubbles and in the presence of protons H^(+) in the continuous phase. Our goal is to understand the link between the reaction kinetics and the transfer of the three reactants present in three different phases in the foam by monitoring the foam structure using simple experimental tools. Measuring the bubble size evolution and the foam liquid fraction enables us to obtain an insight...
Intermediate-Dose Cytarabine as Postinduction AML Therapy
24 juin 2025 02:00 - SFR Icat
CONCLUSIONS: Our trial shows noninferior outcomes in patients 18 to 60 years of age with newly diagnosed AML treated with low- versus high-dose cytarabine; this occurred with similar or lower toxicities. (Funded by the Regional Clinical Research Office, Angers and others; EudraCT number, 2014-000699-24; ClinicalTrials.gov number, NCT02416388.).
Clinical use and reporting of neurofilament quantification in neurological disorders: A global overview
23 juin 2025 02:00 - SFR Icat
INTRODUCTION: Neurofilament light chain (NfL) quantification aids in diagnosing and predicting neurological disorders, but clinical and laboratory practices vary across centers. Differences in result interpretation and reporting further challenge test commutability. This study aimed to review the global analytical and post-analytical methods used for NfL measurement in routine clinical practice across different contexts.
Impact of ureteroscopy on renal function in solitary kidneys: a systematic review
23 juin 2025 02:00 - SFR Icat
CONCLUSION: Ureteroscopy appears to be a viable and safe option for SK patients, presenting minimal risk of long-term renal deterioration. However, only short-term and heterogenous data are available. Future research with standardized methodologies and long-term evaluations are required to validate these findings.
Pregnancy and post-partum psychological disorders
23 juin 2025 02:00 - SFR Icat
No abstract
"Goofballing": An Emerging Threat With Clinical Challenges-A Short Communication
19 juin 2025 02:00 - SFR Icat
CONCLUSIONS: This case highlights the diagnostic challenges associated with the "goofball" phenomenon. The coadministration of methamphetamine and heroin can lead to severe atypical toxicological symptoms. Health care providers should be aware of this emerging practice to ensure rapid diagnosis and appropriate management. Public health initiatives should focus on harm reduction strategies to mitigate associated risks.
A molecular signature predicts hematologic evolution in polycythemia vera patients
18 juin 2025 02:00 - SFR Icat
Genetic analyses have been included in scoring systems to improve the prognostic stratification of hematologic malignancies. Until now, molecular risk scores have not been included into the practical management of patients with polycythemia vera (PV). In this work, we studied 439 PV patients recruited from 15 French centers and described their mutational landscape using high-throughput sequencing. We detected an additional mutation in 53.3% of patients, 22.7% of them having 2 or more mutations....
Morphine and metformin impact immunotherapy benefit in patients with NSCLC: Results of the real-world study IFCT-1502 CLINIVO-SNDS
18 juin 2025 02:00 - SFR Icat
CONCLUSION: Our study confirmed the negative impact of morphine and high-dose corticosteroids on immunotherapy efficacy regardless of poor prognostic factors related to disease aggressiveness. On the other hand, our findings suggested a positive impact of metformin on immunotherapy outcomes.