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Publications

Hypofractionated split-course versus standard radiotherapy in frail older patients with head and neck squamous-cell carcinoma (ELAN-RT trial): a non-inferiority, multicentre, open-label, randomised controlled trial
19 févr. 2026 01:00 - SFR Icat
BACKGROUND: The standard treatment for older patients (aged ≥70 years) with localised, unresectable head and neck squamous-cell carcinoma is standard fractionated radiotherapy (SF-RT). However, its high toxicity and multiple fractions lead physicians to deliver tailored hypofractionated split-course radiotherapy (HSC-RT). The aim of the study was to compare these two radiotherapy methods in older patients.
Extension of the intravitreal injection interval after switching to faricimab in patients with exudative AMD: The multicenter FAR WEST study
18 févr. 2026 01:00 - SFR Icat
CONCLUSION: Switching to faricimab allowed for significantly extending the recurrence-free IVI interval and decreasing the proportion of exudative patients in this cohort. Significant extension was found in a wide range of patients, including those without a loading phase. Further controlled prospective studies are needed to assess the value of a loading phase when switching to faricimab. Safety outcomes were consistent with prior studies.
Clinical value of artificial intelligence in reducing PET image acquisition time: routine clinical validation using qualitative, quantitative, and radiomic analysis on a cohort of 282 patients undergoing [<sup>18</sup>F]FDG and [<sup>68</sup>Ga]Ga-PSMA-11 PET/CT
17 févr. 2026 01:00 - SFR Icat
CONCLUSIONS: SubtlePET® improves the image quality of PET acquisitions performed with reduced acquisition times using [^(18)F]FDG and [^(68)Ga]Ga-PSMA. However, clinician confidence remains limited and, while denoised acquisitions preserve most radiomic features, others are altered, potentially limiting model transposability.
Vasopressor use in septic shock: separating evidence, practice, and future directions
17 févr. 2026 01:00 - SFR Icat
No abstract
Fluid shifts are main drivers for microgravity simulation-induced immune-physiological changes: findings from the VIVALDI studies
16 févr. 2026 01:00 - SFR Icat
Microgravity strongly affects human physiology during spaceflight. Biological sex has not yet been sufficiently considered as a variable for spaceflight deconditioning. The VivalDI studies investigated physiological systems affected by 5-days dry immersion (DI) in females and males, with a focus on immune changes in this report. In both sexes proportions of peripheral granulocytes and NK cells were elevated during DI and T-cell numbers were reduced. Leukocyte activation and cytokine levels were...
Prophylactic Treatment of Patent Ductus Arteriosus With Acetaminophen: A Randomized Clinical Trial
16 févr. 2026 01:00 - SFR Icat
CONCLUSIONS AND RELEVANCE: This study found that prophylactic acetaminophen treatment for patent ductus arteriosus did not increase survival without neonatal morbidities.
Measurement by a numerical approach of breast volume
13 févr. 2026 01:00 - SFR Icat
CONCLUSION: There is a strong correlation between the resection weight and the volume variation measured by the 3D camera, with no influence from breast density. The routine use of a 3D camera would allow plastic surgeons to better plan each surgery and optimize our results.
Corrigendum to "Cutaneous and subcutaneous nodular scedosporiosis in a cat" [J Mycol Med (2026) 101609]
13 févr. 2026 01:00 - SFR Icat
No abstract
Systemic Inflammatory and Hematological Profiles in Triple-Negative Breast Cancer: A Study from a Senegalese Cohort
13 févr. 2026 01:00 - SFR Icat
Background/Objectives: Triple-negative breast cancer (TNBC) is an aggressive subtype associated with a poor prognosis and limited treatment options. Inflammatory and hematological biomarkers have emerged as potential tools for disease characterization, particularly in low-resource settings. Methods: This cross-sectional analytical study was conducted between July 2022 and February 2024 at Dalal Jamm Hospital in Dakar, Senegal, and included 120 women: 40 with TNBC, 40 with hormone-dependent...
Effects of microplastics in CPAP users: looking for needles in the haystack?
12 févr. 2026 01:00 - SFR Icat
No abstract
Early Maturation of Heart Rate Variability in Very Preterm Infants Depends on Neonatal Factors and Is Associated With Neurodevelopmental Risk
12 févr. 2026 01:00 - SFR Icat
CONCLUSION: ΔHRV, early and non-invasively estimated, depends on GA, perinatal and postnatal complications. Its assessment could contribute to evaluation of neurodevelopmental risk.
Exploratory assessment of phosphorylated TDP-43 immunoreactivity in minor salivary glands of patients with ALS
10 févr. 2026 01:00 - SFR Icat
No abstract
Management of urinary fistulas after partial nephrectomy: results from the U-LEAK study (UroCCR-181)
10 févr. 2026 01:00 - SFR Icat
CONCLUSION: We did not observe a significant difference in the time to resolution of urinary fistulas after partial nephrectomy between patients managed interventionally and those managed without any drainage.
Serum gastrin levels, stratified on PPI use, improve diagnosis of pernicious anemia in the absence of intrinsic factor antibodies
10 févr. 2026 01:00 - SFR Icat
CONCLUSION: In B12 deficient patients with isolated APCA, gastrin improves non-invasive diagnosis of pernicious anemia and may reduce the need for endoscopy by helping exclude the diagnosis.
Identification of Novel and Known Variants in Epigenetic Genes Associated with Syndromic 46,XY Differences of Sex Development among Moroccan Patients
10 févr. 2026 01:00 - SFR Icat
CONCLUSION: Our findings highlight the utility of WES in discriminating clinically overlapping syndromic 46,XY DSD to provide an accurate diagnosis, thus allowing better follow-up and appropriate patient management. In addition, our study enriched the mutational spectrum of syndromic 46,XY DSD and confirmed the genotype-phenotype correlations.