Index
>Publications

Publications

Prevalence and risk factors of significant persistent pain symptoms after critical care illness: a prospective multicentric study
24 mai 2023 02:00 - SFR Icat
CONCLUSIONS: Persistent pain symptoms were frequent in critical illness survivors and specialized management remained infrequent. Innovative approaches must be developed in the ICU to minimize the consequences of pain.
Factors associated with early relapse of infantile haemangioma in children treated for at least six months with oral propranolol: A case-control study using the 2014-2021 French Ouest DataHub
24 mai 2023 02:00 - SFR Icat
CONCLUSION: The risk factors for late and early relapse are probably different. Investigation of the risk factors for early vs. late IH relapse is now warranted.
Changes in inflammatory markers in patients treated for Buruli ulcer and their ability to predict paradoxical reactions
23 mai 2023 02:00 - SFR Icat
Mycobacterium ulcerans causes Buruli ulcer, the third most frequent mycobacterial disease after tuberculosis and leprosy. Transient clinical deteriorations, known as paradoxical reactions, occur in some patients during or after antibiotic treatment. We investigated the clinical and biological features of PRs in a prospective cohort of BU patients from Benin including forty-one patients. Neutrophil counts decreased from baseline to day 90 and IL-6, G-CSF and VEGF were the cytokines displaying a...
An Overview of 10 Years of Activity of a Molecular Laboratory for Buruli Ulcer Diagnosis at a Field Hospital in Benin
22 mai 2023 02:00 - SFR Icat
Buruli ulcer (BU) is a neglected tropical disease caused by Mycobacterium ulcerans. Early diagnosis is crucial to prevent morbidity. In November 2012, a field laboratory fully equipped for the rapid on-site quantitative PCR (qPCR) diagnosis of M. ulcerans was established at the Buruli ulcer treatment center (CDTLUB) center in Pobè Benin, a region where BU is endemic. We describe its first 10 years of activity and its gradual evolution into an expert laboratory for BU diagnosis. From 2012 to...
MAGT1 deficiency in XMEN disease is associated with severe platelet dysfunction and impaired platelet glycoprotein N-glycosylation
19 mai 2023 02:00 - SFR Icat
CONCLUSIONS: Our results highlight prominent platelet dysfunction related to MAGT1 deficiency and a defective N-glycosylation in several platelet proteins, that could explain the hemorrhages reported in XMEN patients.
Factors Associated With Weight Loss After Laparoscopic Adjustable Gastric Banding in Adolescents With Severe Obesity
18 mai 2023 02:00 - SFR Icat
CONCLUSION: Comorbidities mostly improved 24 months after LAGB and no major complication occurred. Having lost weight before surgery was associated with a successful surgery, whereas a high body mass index at surgery increases the risk of failure.
Management of renal replacement therapy among adults in French intensive care units: A bedside practice evaluation
15 mai 2023 02:00 - SFR Icat
CONCLUSIONS: Practices in French ICUs are largely compliant with current national guidelines and international literature. The findings should be interpreted in light of the limitations inherent to this type of study.
Prospective Comparison of Thulium and Holmium Laser Lithotripsy for the Treatment of Upper Urinary Tract Lithiasis
15 mai 2023 02:00 - SFR Icat
CONCLUSIONS: TFL and Ho:YAG lithotripsy are comparable in terms of the SF rate and safety for the treatment of UUT lithiasis. According to our study, for a cumulative stone size of 1-2 cm, TFL is more effective than Ho:YAG.
Importance of consultations using mobile teams in the screening and treatment of neglected tropical skin diseases in Benin
12 mai 2023 02:00 - SFR Icat
CONCLUSION: This sustainable approach could help to decrease the burden of skin NTDs in resource-limited countries.
Giant Cell Tumors With HMGA2::NCOR2 Fusion: Clinicopathologic, Molecular, and Epigenetic Study of a Distinct Entity
12 mai 2023 02:00 - SFR Icat
Giant cell tumors (GCTs) with high mobility group AT-Hook 2 (HMGA2)::nuclear receptor corepressor 2 (NCOR2) fusion are rare mesenchymal tumors of controversial nosology, which have been anecdotally reported to respond to CSFR1 inhibitors. Here, we performed a comprehensive study of 6 GCTs with HMGA2::NCOR2 fusion and explored their relationship with other giant cell-rich neoplasms. Tumors occurred in 4 females and 2 males ranging in age from 17 to 32 years old (median 24). Three lesions...
Pediatric Tumors and Developmental Anomalies: A French Nationwide Cohort Study
11 mai 2023 02:00 - SFR Icat
CONCLUSIONS: In the first TED analysis, three major themes have been identified: 1) germline mutations with or without known cancer predisposition, 2) post-zygotic events responsible for genomic mosaicism, 3) coincidental associations. New pathways involved in cancer development need to be investigated to improve our understanding of childhood cancers.
Dedifferentiated cells obtained from glioblastoma cell lines are an easy and robust model for mesenchymal glioblastoma stem cells studies
11 mai 2023 02:00 - SFR Icat
Glioblastoma is an aggressive brain tumor with a poor prognosis. Glioblastoma Stem Cells (GSC) are involved in glioblastoma resistance and relapse. Effective glioblastoma treatment must include GSC targeting strategy. Robust and well defined in vitroGSC models are required for new therapies evaluation. In this study, we extensively characterized 4 GSC models obtained by dedifferentiation of commercially available glioblastoma cell lines and compared them to 2 established patient derived GSC...
Impact of childhood leukemia on siblings: their long-term perception of family functioning and its relationship with their psychosocial characteristics using structural equation modeling
10 mai 2023 02:00 - SFR Icat
CONCLUSIONS: Our study contributed to identifying siblings at risk of facing family issues and reinforced the need to provide more consideration and suitable resources to avoid late consequences. Often considered as the "forgotten children", future research should focus on developing targeted interventions to facilitate family communication and improve siblings' social support.
Corrigendum to "Low complement levels are related to poor obstetric outcomes in women with obstetric antiphospholipid syndrome. The EUROAPS Registry Study Group" [Placenta. 136 (2023 Apr 3) 29-34]
5 mai 2023 02:00 - SFR Icat
No abstract
Gain-of-function variants in the KDF1 gene cause hidradenitis suppurativa associated with ectodermal dysplasia by stabilizing IκB kinase α
5 mai 2023 02:00 - SFR Icat
No abstract