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Publications

Missed Opportunity for Fibrinolysis in ST-Segment-Elevation Myocardial Infarction: The Nationwide France-PCI Registry
13 mars 2026 01:00 - SFR Icat
CONCLUSIONS: In this national STEMI network, more than half of delayed PPCI in eligible early presenters represented a persistent missed-fibrinolysis gap. Routine audit of delayed PCI and missed fibrinolysis as system-level quality metrics should guide time-based pre-hospital triage and align reperfusion with guideline-recommended targets.
Association of sleep-related hypoxemia with survival in patients with non-small cell lung cancer - the NEOSAS-GFPC study group
11 mars 2026 01:00 - SFR Icat
BACKGROUND: Obstructive sleep apnea (OSA) and its hypoxia-related consequences are associated with an increased lung cancer risk.
Dynamic Light Scattering Method Using Derived Count Rate to Accurately Quantify Lipid Nanoparticle Concentration─A Double-Blind Study
11 mars 2026 01:00 - SFR Icat
The rapid advancement of nanomedicine, particularly underscored by the clinical success of lipid nanoparticle (LNP)-based vaccines, has intensified the need for simple, accurate, and widely accessible analytical techniques. A critical yet often overlooked parameter in nanoparticle development is the precise determination of the nanoparticle concentration. Conventional methods such as nanoparticle tracking analysis and electron microscopy are costly, low-throughput, and unavailable in most...
Robot-assisted versus open surgery for multiple ipsilateral renal tumors: a multicenter matched cohort study (UroCCR-60)
9 mars 2026 01:00 - SFR Icat
No abstract
Poly(2-oxazoline)-Based Lipid Nanocapsules Containing Free Hydroxyl Group as Promising Alternative to Conventional PEG-Lipid Nanocapsules
9 mars 2026 01:00 - SFR Icat
Lipid nanocapsules (LNCs) are attractive nanocarriers owing to their high colloidal stability and cytocompatibility. However, their current formulation relies on the poly-(ethylene glycol) (PEG)-based surfactant Kolliphor HS 15, whose clinical use is increasingly compromised by the emergence of anti-PEG antibodies leading to rapid clearance of PEGylated treatments. Poly-(2-oxazoline)-s (POx) share various similarities with PEG such as stealth properties, neutrality, high water solubility,...
Impact of the 2023 ACR/EULAR antiphospholipid syndrome criteria in 1200 women with prior obstetric antiphospholipid syndrome
9 mars 2026 01:00 - SFR Icat
CONCLUSION: The 2023 ACR/EULAR classification criteria substantially reduce the proportion of women with prior obstetric APS who remain classifiable in our cohort. Although these findings highlight a marked decrease in case identification compared with the Sydney criteria, the potential clinical and research implications of this reduction warrant further evaluation in prospective studies.
Revue de presse
9 mars 2026 01:00 - SFR Icat
No abstract
Comparison of traditional and new treatments for fibrous dysplasia: a systematic review and meta-analysis
6 mars 2026 01:00 - SFR Icat
CONCLUSION: Denosumab has shown promising results in recent years in terms of reducing the size and activity of fibrous dysplasia lesions and improving bone markers. Further research is needed to better prevent the serious side effects sometimes associated with this treatment.
Compressive Coronary Hematoma in an Elderly Woman Receiving Oral Anticoagulation Treated With Cutting Balloon Fenestration
4 mars 2026 01:00 - SFR Icat
BACKGROUND: Intramural hematoma (IMH) is an uncommon cause of acute coronary syndrome and may occur in elderly patients with vascular fragility receiving oral anticoagulation.
Mycological diagnosis of superficial fungal infections: French ANOFEL/LABAC recommendations
26 févr. 2026 01:00 - SFR Icat
Superficial fungal infections, mainly caused by dermatophytes but also by yeasts or molds, exhibit wide clinical variability and are a common reason for medical consultation. Recent epidemiological trends, particularly the emergence of extensive cutaneous dermatophytoses, -highlight the need for rigorous mycological diagnosis. The development of nucleic acid amplification techniques (NAAT) and advances in proteomics (MALDI-TOF) have prompted a reassessment of the role of conventional methods,...
Assessment of residual stainless steel surface contamination in an anticancer drug preparation microbiological safety cabinet after decontamination with four cleaning solutions
25 févr. 2026 01:00 - SFR Icat
CONCLUSIONS: Quaternary ammonium-based solutions appear to be the best options for limiting chemocontamination. Despite the similar effectiveness of Septalkan and Surfa'Safe, the latter seems to be a more efficient option for routine use of an appropriate cleaning solution.
Low-Dose Rivaroxaban to Prevent Left Ventricular Thrombosis After Anterior Myocardial Infarction: The APERITIF Randomized Clinical Trial
25 févr. 2026 01:00 - SFR Icat
CONCLUSIONS AND RELEVANCE: In this multicenter randomized clinical trial among patients with anterior STEMI, the addition of low-dose rivaroxaban to DAPT did not demonstrate a statistically significant reduction in LV thrombus formation at 1 month but did increase minor bleeding. Given the limited power of the study, these findings should be interpreted with caution, as a modest effect cannot be excluded.
Mitofusin MFN2 acts as a molecular sensor preventing protein aggregation and mitophagy, with a protective effect against apoptosis in Charcot-Marie-Tooth type 2A disease
25 févr. 2026 01:00 - SFR Icat
Mitochondria are central hubs for cellular fitness, empowered by plastic remodeling of their shape, proteome composition, and/or metabolic state. MFN2 (mitofusin 2) mediates mitochondrial fusion and ensures adaptations in response to metabolic changes and stresses. Besides this canonical role, MFN2 serves as a communication hub with other organelles. It tethers mitochondria to the endoplasmic reticulum (ER), lipid droplets, and peroxisomes, regulating calcium buffering, apoptosis, lipid...
Sleep Apnea-Specific Hypoxic Burden and Postoperative Outcomes of Major Noncardiothoracic Surgery
24 févr. 2026 01:00 - SFR Icat
CONCLUSIONS AND RELEVANCE: Among OSA patients undergoing major noncardiothoracic surgery, SASHB was significantly associated with the risk of 30-day postoperative mortality and CV complications. Further research is needed to determine whether interventions guided by SASHB scores can modify postoperative risk in patients with OSA.
Hypofractionated split-course versus standard radiotherapy in frail older patients with head and neck squamous-cell carcinoma (ELAN-RT trial): a non-inferiority, multicentre, open-label, randomised controlled trial
19 févr. 2026 01:00 - SFR Icat
BACKGROUND: The standard treatment for older patients (aged ≥70 years) with localised, unresectable head and neck squamous-cell carcinoma is standard fractionated radiotherapy (SF-RT). However, its high toxicity and multiple fractions lead physicians to deliver tailored hypofractionated split-course radiotherapy (HSC-RT). The aim of the study was to compare these two radiotherapy methods in older patients.