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Publications

Anti Phospholipase A2 Receptor 1 Antibodies and Membranous Nephropathy Recurrence After Kidney Transplantation
19 déc. 2024 01:00 - SFR Icat
CONCLUSION: The presence of anti-PLA2R1 antibodies prior to transplantation was a strong predictor of recurrence of allograft membranous nephropathy. An individualized immunomonitoring and management strategy for kidney transplant candidates with anti-PLA2R1-associated membranous nephropathy should be considered.
Organisational Changes and Psychosocial Work Factors: Prospective Findings From the National French Working Conditions Survey
19 déc. 2024 01:00 - SFR Icat
The studies exploring the mechanisms by which organisational changes may impact health outcomes are lacking. The objectives of the study were to examine the prospective associations of organisational changes with the deterioration of psychosocial work factors. The study was based on the prospective data of the national French working conditions survey collected in 2013, 2016, and 2019. The study sample included 5200 employees working in the private sector. A large set of organisational changes...
A 2024 inventory in oncology news
17 déc. 2024 01:00 - SFR Icat
The editorial board of the Bulletin du Cancer has compiled a summary of the news from 2024 in oncology, based on the main results presented at international congresses or published over the past year. After a year marked by the success of the Olympic Games, the selection of data is presented and discussed in podiums of three main results by topic. Emphasis is placed on studies that have an immediate impact on practice and on data that raise important questions for the year 2025.
Lost in translocation!
17 déc. 2024 01:00 - SFR Icat
No abstract
Post-operative bleeding in myocardial revascularization under cardiopulmonary bypass for patients treated with aspirin or dual antiplatelet therapy using reduced goal-directed anticoagulation
14 déc. 2024 01:00 - SFR Icat
CONCLUSIONS: Despite higher bleeding under DAPT compared to ASA alone, OpECC with RGDA alleviated severe bleeding which remained low in patients undergoing CABG.
Cost-effectiveness analysis of simulation-based training in transoesophageal echocardiography: Insights from the SIMULATOR randomized clinical trial
12 déc. 2024 01:00 - SFR Icat
No abstract
Becoming an occupational health nurse
12 déc. 2024 01:00 - SFR Icat
Since March 2023, occupational health nurses have been required to have a professional license, a master's degree or an inter-university diploma. They are required to take over 200 hours of theoretical courses, and to complete one or more internships equivalent to over 100 hours.
Evaluating the Benefit of Home Support Provider Services for Positive Airway Pressure Therapy in Patients with Obstructive Sleep Apnoea: Protocol for an Ambispective International Real-World Study
12 déc. 2024 01:00 - SFR Icat
CONCLUSIONS: The AWAIR study has a unique design, leveraging an unprecedented number of eligible participants, decentralised technologies and a real-world comparative methodology across multiple countries. This approach will highlight inter-country differences in terms of patient characteristics, PAP adherence and persistence, as well as PROs, PREs and satisfaction with the HSP service. By assessing the added value of HSP services, the results will support best practices for patient management...
The BRAHMA-associated SWI/SNF chromatin remodeling complex controls Arabidopsis seed quality and physiology
11 déc. 2024 01:00 - SFR Icat
The SWI/SNF (SWItch/Sucrose Non-Fermentable) chromatin remodeling complex is involved in various aspects of plant development and stress responses. Here, we investigated the role of BRM (BRAHMA), a core catalytic subunit of the SWI/SNF complex, in Arabidopsis thaliana seed biology. brm-3 seeds exhibited enlarged size, reduced yield, increased longevity, and enhanced secondary dormancy, but did not show changes in primary dormancy or salt tolerance. Some of these phenotypes depended on the...
Opa1 and MT-Nd6 mutations induce early mitochondrial changes in the retina and prelaminar optic nerve of hereditary optic neuropathy mouse models
11 déc. 2024 01:00 - SFR Icat
Hereditary optic neuropathies, including dominant optic atrophy and Leber's hereditary optic neuropathy, are genetic disorders characterized by retinal ganglion cell degeneration leading to vision loss, mainly associated with mitochondrial dysfunction. In this study, we analysed mitochondrial distribution and ultrastructure in the retina and longitudinal optic nerve sections of pre-symptomatic hereditary optic neuropathies mouse models with Opa1 and Nd6 deficiency to identify early mitochondrial...
Harnessing the spatial and transcriptional regulation of monoterpenoid indole alkaloid metabolism in Alstonia scholaris leads to the identification of broad geissoschizine cyclase activities
10 déc. 2024 01:00 - SFR Icat
Monoterpene indole alkaloids (MIAs) are valuable metabolites produced in numerous medicinal plants from the Apocynaceae family such as Alstonia scholaris, which synthesizes strictamine, a MIA displaying neuropharmacological properties of a potential importance. To get insights into the MIA metabolism in A. scholaris, we studied here both the spatial and transcriptional regulations of MIA genes by performing a robust transcriptomics analysis of the main plant organs, leaf epidermis but also by...
Science around the world
9 déc. 2024 01:00 - SFR Icat
No abstract
Impact of caesarean scar defects on the success of assisted human reproduction: the NICHE-ART prospective French cohort study protocol
7 déc. 2024 01:00 - SFR Icat
BACKGROUND: The global increase in caesarean sections (CS), currently at 21.1% of all deliveries, has led to a rise in uterine scar defects, or 'niches', at the hysterotomy site. These niches, detectable in 13%-84% of cases via transvaginal ultrasound (TVS) and 42%-84% through sonohysterography (SHG), may contribute to gynaecological complications, including abnormal uterine bleeding, chronic pain and secondary infertility. Niche-associated risks for in vitro fertilisation (IVF) outcomes remain...
A GAME changer in steroidal metabolite biosynthesis
5 déc. 2024 01:00 - SFR Icat
No abstract
T-cell-related skin inflammatory flareups with Th1 polarity in a patient with pseudoxanthoma elasticum
3 déc. 2024 01:00 - SFR Icat
Pseudoxanthoma elasticum (PXE) is a genetic disorder characterized by ectopic calcification of tissues rich in elastic fibres (OMIM 264800). To date, PXE is considered a metabolic disease linked to an imbalance between pro- and anti-calcifying factors. The occurrence of sporadic erythematous flareups of PXE skin lesions is a complaint that we heard about on several occasions at the French PXE reference centre. However, this rare clinical aspect had never been extensively studied. We have had the...